Abstract Mitochondrial Ca2+ overload can mediate mitochondria-dependent cell death, a major contributor to several Shipping Protection human diseases.Indeed, Duchenne muscular dystrophy (MD) is driven by dysfunctional Ca2+ influx across the sarcolemma that causes mitochondrial Ca2+ overload, organelle rupture, and muscle necrosis.The mitochondrial
Safety and antibody response to two-dose SARS-CoV-2 messenger RNA vaccination in patients with multiple myeloma
Abstract Background Patients with multiple myeloma (MM) were excluded from the original SARS-CoV-2 mRNA vaccine trials, which may Brake Pedal influence vaccine hesitancy in this population.We prospectively characterized the safety and immunogenicity of two-dose SARS-CoV-2 mRNA vaccination in 44 patients with MM, who underwent vaccination from 12/17
Characterization of Dendritic Cell-Derived Extracellular Vesicles During Dengue Virus Infection
The dengue virus (DENV), transmitted by Aedes spp.mosquitoes, is one of the most important arboviral infections in the world.Dengue begins as a febrile condition, and in certain patients, it can evolve severe clinical outcomes, such as dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS).The reasons why certain patients develop DHF or DSS
HPAStainR: a Bioconductor and Shiny app to query protein expression patterns in the Human Protein Atlas [version 2; peer review: 1 approved, 2 approved with reservations]
The Human Protein Atlas is a website of protein expression in Shipping Protection human tissues.It is an excellent resource of tissue and cell type protein localization, but only allows the query of a single protein at a time.We introduce HPAStainR as a new Shiny app and Bioconductor/R package used to query the scored staining patterns in the Human